SSRIs and Heat: What You Need to Know This Summer

SSRI Summertime

Summer brings longer days, sunshine, and higher temperatures—but if you’re taking a selective serotonin reuptake inhibitor (SSRI), it also brings unique health considerations. SSRIs are commonly prescribed antidepressants, and while they’re very safe, they can interact with heat in ways that increase health risks.

💊 What Are SSRIs?

SSRIs (e.g., fluoxetine, sertraline, citalopram, escitalopram, and paroxetine) help manage depression, anxiety, and other mental health conditions by increasing serotonin levels in the brain. They’re among the most prescribed psychiatric medications in the U.S.

☀️ How SSRIs Can Affect You in the Heat

  1. Impaired Thermoregulation
    SSRIs can interfere with the body’s ability to regulate temperature. This means you may not sweat as effectively, making it harder for your body to regulate its temperature.

  2. Increased Risk of Dehydration
    SSRIs can sometimes cause side effects like nausea or diarrhea, which—combined with summer heat—may lead to faster fluid loss and dehydration.

  3. Photosensitivity
    Some SSRIs, such as sertraline (Zoloft), may increase your skin’s sensitivity to sunlight, increasing the risk of sunburn.

  4. Risk of Serotonin Syndrome
    Although rare, extreme heat or combining multiple serotonergic medications can raise the risk of serotonin syndrome, a potentially life-threatening condition.

Other Things to Consider

Children, older adults, and those on multiple medications are at greater risk.
SSRIs can be used in addition to other medications, some increasing the chance of heat-related illness.

. Symptoms of heat intolerance can be subtle.
Watch for symptoms such as dizziness, confusion, nausea, headache, dry skin, or lack of sweating, as these may indicate heat exhaustion or heatstroke.


🌡 Stay Safe in the Heat: Tips for SSRI Users

  • Stay Hydrated: Drink water throughout the day—even if you’re not thirsty. Avoid excessive caffeine and alcohol, which can dehydrate you.

  • Limit Time in Direct Sunlight: especially during peak hours (10 AM–4 PM).

  • Dress Smart: Lightweight, breathable clothing helps your body regulate temperature.

  • Watch for Warning Signs: Dizziness, excessive sweating (or lack thereof), confusion, or nausea could indicate overheating or dehydration.

  • Talk to Your Provider: Always inform your provider if you’re experiencing heat-related symptoms or side effects from your medication.


🧠 Mental Health Matters All Year Long

Your mental health doesn’t take a summer break. Whether you’re managing depression, anxiety, or another condition, Journey Healthcare is here for you, offering personalized psychiatric care year-round.

📍 Serving patients across Pennsylvania – virtually and in person. Two Pittsburgh locations: Murrysville and Green Tree, PA.
🌐 www.journeyhealthcare.com

If you feel like you’d benefit from psychiatric evaluation or medication management for mental health symptoms, please complete the form below.

Providers: Submit referral here!